Ephrin A5 (EFNA5) Rabbit Polyclonal Antibody

CAT#: TA351160

Rabbit Polyclonal Anti-EFNA5 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human EFNA5
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ephrin A5
• Database Link:
  NP_001953
  Entrez Gene 13640 MouseEntrez Gene 116683 RatEntrez Gene 1946 Human
  UniProt ID P52803
• Background: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997).
• Synonyms: AF1; EFL5; EPLG7; GLC1M; LERK7; RAGS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance