HINT1 Rabbit Polyclonal Antibody

CAT#: TA351246

Rabbit Polyclonal Anti-HINT1 Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: LoVo cells Primary antibody: TA351246 (HINT1 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 15 seconds

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA351246 (HINT1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA351246 (HINT1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351246 (HINT1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351246 (HINT1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 25-100
  Positive control: Human colorectal cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human HINT1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 14 kDa
• Gene Name: histidine triad nucleotide binding protein 1
• Database Link:
  NP_005331
  Entrez Gene 15254 MouseEntrez Gene 690660 RatEntrez Gene 3094 Human
  UniProt ID P49773
• Background: The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.
• Synonyms: HINT; NMAN; PKCI-1; PRKCNH1