KDM4A Rabbit Polyclonal Antibody

CAT#: TA351310

Rabbit Polyclonal Anti-KDM4A Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: NIH/3T3 cells and mouse liver tissue
  IHC: 50-200
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human KDM4A
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 121 kDa
• Gene Name: lysine demethylase 4A
• Database Link:
  NP_055478
  Entrez Gene 230674 MouseEntrez Gene 9682 Human
  UniProt ID O75164
• Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
• Synonyms: JHDM3A; JMJD2; JMJD2A; TDRD14A

Reference Data

• Protein Families: Druggable Genome, Transcription Factors