PIM3 Rabbit Polyclonal Antibody

CAT#: TA351349

Rabbit Polyclonal Anti-PIM3 Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Mouse skeletal muscle tissue, Primary antibody: (PIM3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes

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  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (PIM3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using (PIM3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PIM3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: Pim-3 proto-oncogene, serine/threonine kinase
• Database Link:
  NP_001001852
  Entrez Gene 223775 MouseEntrez Gene 415116 Human
  UniProt ID Q86V86
• Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
• Synonyms: pim-3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase