MLK3 (MAP3K11) Rabbit Polyclonal Antibody
Other products for "MAP3K11"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 500-2000 WB positive control: PC3, hela and A549 cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MAP3K11 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 93 kDa |
Gene Name | mitogen-activated protein kinase kinase kinase 11 |
Database Link | |
Background | The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. |
Synonyms | MEKK11; MLK-3; MLK3; PTK1; SPRK |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway |
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