NDUFAB1 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 100-300 Positive control: Human lung cancer Predicted cell location: Cytoplasm and Nucleus |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human NDUFAB1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | NADH:ubiquinone oxidoreductase subunit AB1 |
Database Link | |
Background | NDUFAB1 (NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1), also known as SDAP, ACP (acyl carrier protein) or FASN2A, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain. Consisting of 156 amino acids and localizing to mitochondria, NDUFAB1 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I). Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. NDUFAB1 contains one acyl carrier domain and is encoded by a gene that maps to human chromosome 16p12.2 and mouse chromosome 7 F3. |
Synonyms | ACP; FASN2A; SDAP |
Reference Data | |
Protein Pathways | Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
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