MMP9 Rabbit Polyclonal Antibody

CAT#: TA351482

Rabbit Polyclonal Anti-MMP9 Antibody

Product Images

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (MMP9 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (MMP9 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1000-2000, IHC: 25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MMP9
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 9
• Database Link:
  NP_004985
  Entrez Gene 17395 MouseEntrez Gene 81687 RatEntrez Gene 4318 Human
  UniProt ID P14780
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
• Synonyms: CLG4B; GELB; MANDP2; MMP-9

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Bladder cancer, Leukocyte transendothelial migration, Pathways in cancer