P70 S6 Kinase beta (RPS6KB2) Rabbit Polyclonal Antibody

CAT#: TA351487

Rabbit Polyclonal Anti-RPS6KB2 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution IHC: 50-200
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human RPS6KB2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 53 kDa
Gene Name ribosomal protein S6 kinase B2
Background This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Synonyms KLS; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; S6K-beta2; S6K2; SRK; STK14B
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway

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