PCSK9 Rabbit Polyclonal Antibody

CAT#: TA351505

Rabbit Polyclonal Anti-PCSK9 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: Human rectal cancer tissue Jurkat cells HT29 cells Primary antibody: TA351505 (PCSK9 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells
  IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PCSK9
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 74 kDa
• Gene Name: proprotein convertase subtilisin/kexin type 9
• Database Link:
  NP_777596
  Entrez Gene 100102 MouseEntrez Gene 298296 RatEntrez Gene 255738 Human
  UniProt ID Q8NBP7
• Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation.
• Synonyms: FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9

Reference Data

• Protein Families: Secreted Protein