Plectin (PLEC) Rabbit Polyclonal Antibody

CAT#: TA351536

Rabbit Polyclonal Anti-PLEC Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351536 (PLEC Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351536 (PLEC Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PLEC
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: plectin
• Database Link:
  NP_000436
  Entrez Gene 18810 MouseEntrez Gene 64204 RatEntrez Gene 5339 Human
  UniProt ID Q15149
• Background: Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes.
• Synonyms: EBS1; EBSO; HD1; LGMD2Q; PCN; PLEC1; PLEC1b; PLTN

Reference Data

• Protein Families: Druggable Genome