PPM1F Rabbit Polyclonal Antibody

CAT#: TA351551

Rabbit Polyclonal Anti-PPM1F Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "PPM1F"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: K562 cells and human fetal liver tissue
IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human PPM1F
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 50 kDa
Gene Name protein phosphatase, Mg2+/Mn2+ dependent 1F
Background The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Synonyms CAMKP; CaMKPase; FEM-2; hFEM-2; POPX2
Reference Data
Protein Families Druggable Genome, Phosphatase

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