CD71 (TFRC) Rabbit Polyclonal Antibody

CAT#: TA351573

Rabbit Polyclonal Anti-TFRC Antibody

Product Images

Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: K562 cells, Jurkat cells, Primary antibody: (TFRC Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

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  The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (TFRC Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TFRC
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 85 kDa
• Gene Name: transferrin receptor
• Database Link:
  NP_003225
  Entrez Gene 22042 MouseEntrez Gene 64678 RatEntrez Gene 7037 Human
  UniProt ID P02786
• Background: Transferrin receptor protein 1 (TfR1) also known as (Cluster of Differentiation 71) (CD71) is a protein that in humans is encoded by the TFRC gene. TfR1 is required for iron delivery from transferrin to cells. TfR1 is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis.
• Synonyms: CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage