ROR alpha (RORA) Rabbit Polyclonal Antibody

CAT#: TA351609

Rabbit Polyclonal Anti-RORA rabbit polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: TM4 cells
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RORA
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59 kDa
• Gene Name: RAR related orphan receptor A
• Database Link:
  NP_002934
  Entrez Gene 6095 Human
  UniProt ID P35398
• Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm.
• Synonyms: NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors