SIAH2 Rabbit Polyclonal Antibody

CAT#: TA351662

Rabbit Polyclonal Anti-SIAH2 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA351662 (SIAH2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA351662 (SIAH2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351662 (SIAH2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351662 (SIAH2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SIAH2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: siah E3 ubiquitin protein ligase 2
• Database Link:
  NP_005058
  Entrez Gene 20439 MouseEntrez Gene 140593 RatEntrez Gene 6478 Human
  UniProt ID O43255
• Background: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.
• Synonyms: hSiah2

Reference Data

• Protein Families: Druggable Genome, Transcription Factors