SLC5A6 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm or Cell membrane |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human SLC5A6 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | solute carrier family 5 member 6 |
Database Link | |
Background | SLC5A6 is a 635 amino acid protein that belongs to the sodium-coupled glucose transporter family. SMVT contains 12 putative transmembrane domains with the N and C termini both facing towards the cytoplasm. Its function is to transport the essential vitamins pantothenate, biotin, and the metabolite lipoate into cells of various human tissues. Biotin, also known as vitamin B6, is important in synthesizing fatty acids gluconeogenesis, and metabolizing leucine, while pantothenate, or vitamin B5, is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. Lipoate is involved in oxidative metabolism. |
Synonyms | SMVT |
Reference Data | |
Protein Families | Transmembrane |
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