SLIT1 Rabbit Polyclonal Antibody

CAT#: TA351719

Rabbit Polyclonal Anti-SLIT1 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SLIT1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: slit guidance ligand 1
• Database Link:
  NP_003052
  Entrez Gene 20562 MouseEntrez Gene 65047 RatEntrez Gene 6585 Human
  UniProt ID O75093
• Background: Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene. Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions By similarity. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
• Synonyms: MEGF4; SLIL1; SLIT-1; SLIT3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance