SRGAP2 Rabbit Polyclonal Antibody

CAT#: TA351753

Rabbit Polyclonal Anti-SRGAP2 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351753 (SRGAP2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351753 (SRGAP2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: K562, 231, Raji and hela cells
  IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SRGAP2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SLIT-ROBO Rho GTPase activating protein 2
• Database Link:
  NP_056141
  Entrez Gene 14270 MouseEntrez Gene 360840 RatEntrez Gene 23380 Human
  UniProt ID O75044
• Background: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.
• Synonyms: ARHGAP34; FNBP2; SRGAP2A; SRGAP3

Reference Data

• Protein Pathways: Axon guidance