Sulfatase 1 (SULF1) Rabbit Polyclonal Antibody

CAT#: TA351768

Rabbit Polyclonal Anti-SULF1 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351768 (SULF1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351768 (SULF1 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 35-150
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SULF1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sulfatase 1
• Database Link:
  NP_055985
  Entrez Gene 171396 RatEntrez Gene 240725 MouseEntrez Gene 23213 Human
  UniProt ID Q8IWU6
• Background: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
• Synonyms: HSULF-1; SULF-1

Reference Data

• Protein Families: Druggable Genome