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Prothrombin (F2) Rabbit Polyclonal Antibody
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Other products for "F2"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1000-5000 WB positive control: Jurkat and A549 cells, Mouse brain tissue, 293T, LNCap, NIH/3T3 and Hela cells IHC: 30-150 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human F2 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | coagulation factor II, thrombin |
| Database Link | |
| Background | Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. |
| Synonyms | PT; RPRGL2; THPH1 |
| Reference Data | |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.