TNFRSF4 Rabbit Polyclonal Antibody

CAT#: TA351827

Rabbit Polyclonal Anti-TNFRSF4 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Hepg2 cells
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TNFRSF4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: tumor necrosis factor receptor superfamily member 4
• Database Link:
  NP_003318
  Entrez Gene 7293 Human
  UniProt ID P43489
• Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
• Synonyms: ACT35; CD134; IMD16; OX40; TXGP1L

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction