Tryptophan 5 hydroxylase 2 (TPH2) Rabbit Polyclonal Antibody
Other products for "TPH2"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cytoplasm or Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human TPH2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 56 kDa |
Gene Name | tryptophan hydroxylase 2 |
Database Link | |
Background | This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. |
Synonyms | ADHD7; NTPH |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Tryptophan metabolism |
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