UTS2D (UTS2B) Rabbit Polyclonal Antibody

CAT#: TA351907

Rabbit Polyclonal Anti-UTS2B Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-6: A431 cells Human liver cancer tissue Lovo cells PC3 cells Human placenta tissue 293T cells Primary antibody: TA351907 (UTS2B Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351907 (UTS2B Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351907 (UTS2B Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A431 cells and Human liver cancer tissue, Lovo and PC3 cells, Human placenta tissue and 293T cells
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human UTS2B
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 14 kDa
• Gene Name: urotensin 2B
• Database Link:
  NP_937795
  Entrez Gene 257313 Human
  UniProt ID Q765I0
• Background: Potent vasoconstrictor.Human Urotensin II is composed of only 11 amino acid residues, while fish and frog Urotensin II possess 12 and 13 amino acid residues, respectively (2). Human Urotensin II is found within both vascular and cardiac tissue, including coronary atheroma, and effectively constricts isolated arteries from nonhuman primates (3). Urotensin II may act as an autocrine and/or paracrine hormone rather than as a circulating hormone, by playing an important role in the development of ventricular hypertrophy induced by chronic hypoxia (4).
• Synonyms: U2B; URP; UTS2D

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane