WNK1 Rabbit Polyclonal Antibody

CAT#: TA351930

Rabbit Polyclonal Anti-WNK1 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: TM4 cells
  IHC: 10-50
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human WNK1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 251 kDa
• Gene Name: WNK lysine deficient protein kinase 1
• Database Link:
  NP_061852
  Entrez Gene 116477 RatEntrez Gene 232341 MouseEntrez Gene 65125 Human
  UniProt ID Q9H4A3
• Background: This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
• Synonyms: HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase