AP2 alpha (AP2A1) Rabbit Polyclonal Antibody

CAT#: TA351982

Rabbit Polyclonal Anti-AP2A1 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A431, 231 and NIH/3T3 cell
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human AP2A1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 108 kDa
• Gene Name: adaptor related protein complex 2 alpha 1 subunit
• Database Link:
  NP_570603
  Entrez Gene 11771 MouseEntrez Gene 160 Human
  UniProt ID O95782
• Background: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms.
• Synonyms: ADTAA; AP2-ALPHA; CLAPA1

Reference Data

• Protein Pathways: Endocytosis, Huntington's disease