ALIX (PDCD6IP) Mouse Monoclonal Antibody [Clone ID: 3A9]

CAT#: TA352527

Mouse Monoclonal anti-Alix Antibody


USD 155.00

5 Days*

Size
    • 25 ug

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Specifications

Product Data
Clone Name 3A9
Applications WB
Recommended Dilution WB, IP, IF
Reactivities Human, Mouse, and Frog
Host Mouse
Isotype IgG1, kappa
Clonality Monoclonal
Immunogen Recombinant full-length human Alix protein
Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration lot specific
Purification The antibody was purified by affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 95.8 kDa
Gene Name programmed cell death 6 interacting protein
Background Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. The predicted molecular weight is approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. The Bro1 domain interacts with CHMP4b, which is also involved in endosomal sorting.
Synonyms AIP1; ALIX; DRIP4; HP95
Note Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 1 µg/ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Reference Data
Protein Families Druggable Genome
Protein Pathways Endocytosis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.