Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: MD-1]

CAT#: TA352731

Mouse Monoclonal Anti-IFN-gamma Antibody, Biotin conjugated

Specifications

Product Data

• Clone Name: MD-1
• Recommended Dilution: ELISA, ELISPOT, Immunohistochemistry
• Reactivities: Human, Rhesus Macaque
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: IFN-gamma
• Formulation: Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
• Concentration: lot specific
• Purification: Ion exchange chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 16.7 kDa
• Gene Name: interferon, gamma
• Database Link:
  NP_000610
  Entrez Gene 3458 Human
  UniProt ID P01579
• Background: The monoclonal antibody to human IFN-? (clone MD-1) was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-? and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-? (van der Meide P.H. et al. 1985). The MD-1 antibody has been descriped as useful in a sandwich ELISA (Wassenaar A. et al. 1995, Wierenga E.A. et al. 1990 and Yazdanbakhsh M et al. 1993). Further, the antibody has proven to cross react with rhesus macaque IFN-? and can be used for immunohistochemical staining of frozen tissues (Wassenaar A. et al. 1995 and Kap Y. et al. 2009). The MD-1 antibody has been reported for use in intracellular flow cytometric analysis (Hamann D. et al. 1996). Other available formats: unconjugated and FITC labeled.
• Synonyms: IFG; IFI

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus