Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: MD-2]

CAT#: TA352733

Mouse Monoclonal Anti-IFN-gamma Antibody


USD 490.00

3 Weeks*

Size
    • 500 ug

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Specifications

Product Data
Clone Name MD-2
Recommended Dilution ELISA, Immunohistochemistry, Western Blot
Reactivities Human, Rhesus Macaque
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen IFN-gamma
Formulation Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
Concentration lot specific
Purification Ion exchange chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 16.7 kDa
Gene Name interferon, gamma
Background The monoclonal antibody to human IFN-? (clone MD-2) was first described in 1985. It has shown to binds with high affinity to both natural and recombinant human IFN-? but does not neutralize the antiviral bioactivity of IFN-? in vitro. In a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-? (van der Meide P.H. et al. 1985). The MD-2 antibody has been descriped as useful in a sandwich ELISA (van Dissel J.T. et al. 2011, Wassenaar A. et al. 1995 and Wierenga E.A. et al. 1990). Further, the antibody has proven to cross react with rhesus macaque, cynomolgus monkey and marmoset IFN-? and can be used for immunohistochemical staining of frozen tissues (Kap Y. et al. 2009).
Synonyms IFG; IFI
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.