TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: B-C7]

CAT#: TA352747

Mouse Monoclonal Anti-TNF-alpha Antibody

Specifications

Product Data

• Clone Name: B-C7
• Recommended Dilution: ELISA, Intracellular staining, Immunohistochemistry, Neutralization assay
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: TNF-alpha
• Formulation: Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
• Concentration: lot specific
• Purification: Ion exchange chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25.5 kDa
• Gene Name: tumor necrosis factor
• Database Link:
  NP_000585
  Entrez Gene 7124 Human
  UniProt ID P01375
• Background: The monoclonal antibody to human TNF-alpha (clone B-C7) has shown to be suitable for intracellular staining (Birebent B. et al. 1998) and neutralization assays (Hamacher J. et al. 2002 and van Hensbroek M.B. et al. 1996). B-C7 antibody recognizes both natural and recombinant human TNF-alpha and can be used in ELISA (Robinet E. et al. 1997) and immunohistochemistry (Voorzanger N. et al. 1996).
• Synonyms: DIF; TNF-alpha; TNFA; TNFSF2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Allograft rejection, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Asthma, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Fc epsilon RI signaling pathway, Graft-versus-host disease, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Natural killer cell mediated cytotoxicity, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus, Type II diabetes mellitus