Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: MD-1]

CAT#: TA352756

Mouse Monoclonal Anti-IFN-gamma Antibody,Biotin conjugated

Specifications

Product Data

• Clone Name: MD-1
• Recommended Dilution: ELISA, ELISPOT, Flow cytometry, Immunohistochemistry, Neutralization assay, Western Blot
• Reactivities: Rhesus Macaque, Cynomolgus Monkey, Human, Chimpanzee
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: IFN-gamma
• Formulation: Prior to lyophilization: 0.5 ml PBS + 125 mM trehalose.
• Concentration: lot specific
• Purification: Ion exchange chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 16.7 kDa
• Gene Name: interferon, gamma
• Database Link:
  NP_000610
  Entrez Gene 574282 MonkeyEntrez Gene 3458 Human
  UniProt ID P01579
• Background: The neutralizing monoclonal antibody to monkey IFN-? (clone MD-1) was first described in 1985. The MD-1 antibody can be used in a sandwich ELISA and in ELISPOT assays (Aurisicchio L. et al. 2007, Koopman G. et al. 2008, Mäkitalo B. et al. 2002 and van der Meide P.H. et al. 1995). Further, the antibody has been descriped in immunohistochemical staining of frozen tissues of marmosets (Villoslada P. et al. 2000) and in intracellular flow cytometric analysis (Hamann D. et al. 1996). The MD-1 antibody has been reported to cross react with rhesus macaque, pig-tailed macaque, cynomogus monkey, baboon and African green monkey IFN-? and can be used in Luminex systems (Giavedoni L.D. 2005).
• Synonyms: IFG; IFI

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus