CD64 (FCGR1A) Mouse Monoclonal Antibody [Clone ID: 10.1]
CAT#: TA352787L
Mouse monoclonal Anti-FCGR1 Clone 10.1
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Specifications
Product Data | |
Clone Name | 10.1 |
Recommended Dilution | FACS ; FACS ; IHC ; IF ; IP ; Functional |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Rheumatoid synovial fluid cells and fibronectin purified human monocytes. |
Formulation | PBS with 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Purified by affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 71 |
Gene Name | Fc fragment of IgG receptor Ia |
Database Link | |
Background | Fc-gamma receptor 1 (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines. It is a marker of iflammation. It is involved in cancer and many chronic diseases (arthritis, multiple sclerosis, diabetic ulcers), but also in antibody-dependent cell-mediated cytotoxicity (ADCC), sepsis, automimmune disorders and periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. The 10.1 antibody blocks the Ig binding to FcR1 receptor. |
Synonyms | CD64; CD64A; FCRI; IGFR1 |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Fc gamma R-mediated phagocytosis, Hematopoietic cell lineage, Systemic lupus erythematosus |
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