F Mouse Monoclonal Antibody [Clone ID: RSV 11-2-C9]
CAT#: TA352905L
Mouse monoclonal Anti-GlycoproteinF Clone RSV 11-2-C9
Other products for "F"
Specifications
Product Data | |
Clone Name | RSV 11-2-C9 |
Applications | WB |
Recommended Dilution | ELISA ; IF ; WB |
Host | Mouse |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Immunogen | Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C |
Formulation | PBS with 0.02% Sodium Azide |
Concentration | lot specific |
Purification | Purified by affinity chromatography. |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Background | Human Respiratory Syncytial Virus (RSV) is a major cause of lower respiratory tract illness and is the chief cause of hospitalization for respiratory tract illness in young children.The glycoprotein F is located on the surface of viral envelope, its function is to induce fusion of viral envelope with host-cell envelope resulting in syncytium formation. The glycoprotein F (also named VP70, F0 or fusion protein) consists of two components: F1 (also named VPG48) and F2 (also named VGP26) held together by disulphide bonds. The reported molecular weight of the VGP26 component varies between 20 to 26 kDa. |
Note | Immunoblot using the reduced and unreduced RS virus shows that 11-2-C9 reacts with the non-reduced form of the virus F protein (VP70). It has a plaque reduction neutralization titer of 10 2. |
Reference Data |
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