F Mouse Monoclonal Antibody [Clone ID: RSV 11-2-F3]

CAT#: TA352907L

Mouse monoclonal Anti-F Glycoprotein Clone RSV 11-2-F3

Product Images

Western Blot using mAb 11-2-F3. Ag: gradient-purified RS virus.

Specifications

Product Data

• Clone Name: RSV 11-2-F3
• Applications: WB
• Recommended Dilution: ELISA ; IF ; WB
• Reactivities: Virus
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Gradient-purified RSF-44 virus (subgroup A) UV inactivated for 20 minutes at 20C
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Background: Human Respiratory Syncytial Virus (RSV) is a major cause of lower respiratory tract illness and is the chief cause of hospitalization for respiratory tract illness in young children.The glycoprotein F is located on the surface of viral envelope, its function is to induce fusion of viral envelope with host-cell envelope resulting in syncytium formation. The glycoprotein F (also named VP70, F0 or fusion protein) consists of two components: F1 (also named VPG48) and F2 (also named VGP26) held together by disulphide bonds. The reported molecular weight of the VGP26 component varies between 20 to 26 kDa. Immunoblot using the reduced and unreduced RS virus shows that 11-2-F3 reacts with the non-reduced form of the virus F protein (VP70) and the reduced form (F1). It has a plaque reduction neutralization titer of 10 2.2.
• Note: Reactivity: RSF-44 virus (subgroup A)