ADAM17 Rabbit Polyclonal Antibody

CAT#: TA352952L

Rabbit polyclonal anti-ADAM17 antibody

USD 1,255.00

5 Days*

Size
    • 500 ul

Product Images

Other products for "ADAM17"

Specifications

Product Data
Applications WB
Recommended Dilution WB
Reactivities Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen ADAM17
Concentration lot specific
Purification Unpurified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size ~120 kDa
Gene Name ADAM metallopeptidase domain 17
Background ADAM17 (TACE/CD156b) has proved capable of cleaving epidermal growth factor receptor (EGFR) ligands, extracellular Notch1, cell-surface receptors, and adhesion molecules. As proteolytic cleavage is an indispensable activation event for many of these substrates, ADAM17 has emerged as an attractive therapeutic target for the treatment of cancer and rheumatoid arthritis.
Synonyms ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE
Note Suggested dilution for western blot: 1:250
Reference Data
Protein Families Druggable Genome, Protease, Transmembrane
Protein Pathways Alzheimer's disease, Epithelial cell signaling in Helicobacter pylori infection, Notch signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.