Alkaline Phosphatase (ALPI) Mouse Monoclonal Antibody [Clone ID: AAP1]

CAT#: TA352961L

Mouse monoclonal Anti-Alkaline phosphatase Clone AAP1

Specifications

Product Data

• Clone Name: AAP1
• Recommended Dilution: ELISA
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: D98/AH-2 (HeLa) cells, which produce human intestinal alkaline phosphatase ectopically
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: alkaline phosphatase, intestinal
• Database Link:
  NP_001622
  Entrez Gene 248 Human
  UniProt ID P09923
• Background: Alkaline phosphatases are phosphodiesterases which remove phosphate groups from the 5' end of DNA, RNA and proteins at high pH. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.
• Synonyms: IAP
• Note: AAP.1 may be used in the diagnosis of tumours as some tumours produce intestinal ALP ectopically.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Folate biosynthesis, Metabolic pathways