BRCA2 Rabbit Polyclonal Antibody

CAT#: TA353006L

Rabbit polyclonal anti-BRCA2 antibody

Product Images

MTA42 is raised against C-terminus of BRCA2. HeLa cells contain full length BRCA2 whereas Capan-1 cells have a BRCA2 C-terminal truncation.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ChIP ; IP ; WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: BRCA2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 370
• Gene Name: BRCA2, DNA repair associated
• Database Link:
  NP_000050
  Entrez Gene 12190 MouseEntrez Gene 675 Human
  UniProt ID P51587
• Background: Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumour suppressor gene. BRCA2 is involved in the repair of chromosomal damage, specifically in localising Rad51 to double strand breaks. BRCA2 and BRCA1 are frequently mutated in cases of hereditary breast and ovarian cancer.
• Synonyms: BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11
• Note: Suggested dilutions for WB: 1/500 to 1/1000

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination, Pancreatic cancer, Pathways in cancer