CD151 Mouse Monoclonal Antibody [Clone ID: 11G5a]

CAT#: TA353025L

Mouse monoclonal Anti-CD151 Clone 11G5a

Specifications

Product Data

• Clone Name: 11G5a
• Recommended Dilution: ELISA ; FACS ; IHC ; IF ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD151 molecule (Raph blood group)
• Database Link:
  NP_620599
  Entrez Gene 977 Human
  UniProt ID P48509
• Background: Clone 11G5a recognizes the human CD151 cell surface antigen, also known as PETA-3. CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen. CD151 is a cell surface glycoprote ininvolved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells.
• Synonyms: GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24
• Note: CD151 is very closely associated with the alpha3 beta1 integrin in cells and co-immunoprecipitation may occur even in quite stringent conditions (Yauch. et al. 1998).

Reference Data

• Protein Families: Druggable Genome, Transmembrane