CD33 Mouse Monoclonal Antibody [Clone ID: CD33 3D6]

CAT#: TA353038L

Mouse monoclonal Anti-SIGLEC3 Clone CD33 3D6

Specifications

Product Data

• Clone Name: CD33 3D6
• Recommended Dilution: ELISA
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD33-Fc recombinant protein
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD33 molecule
• Database Link:
  NP_001763
  Entrez Gene 945 Human
  UniProt ID P20138
• Background: The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. CD33 is found on granulocyte and macrophage precursors in the bone marrow, but not on pluripotent stem cells. CD33 is also expressed on, and a useful marker for, peripheral monocytes. CD33 is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
• Synonyms: p67; SIGLEC-3; SIGLEC3

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage