Cytochrome P450 1A2 (CYP1A2) Mouse Monoclonal Antibody [Clone ID: D15]

CAT#: TA353117L

Mouse monoclonal Anti-CYP1A2 Clone D15

Specifications

Product Data

• Clone Name: D15
• Recommended Dilution: ELISA ; IHC ; IF ; WB
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MC1a (Preparation C31B4, rat liver cytochrome P4501A2)
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52
• Gene Name: cytochrome P450 family 1 subfamily A member 2
• Database Link:
  NP_000752
  Entrez Gene 13077 MouseEntrez Gene 24297 RatEntrez Gene 1544 Human
  UniProt ID P05177
• Background: In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.
• Synonyms: CP12; P3-450; P450(PA)
• Note: D15 cross reacts with CYP1A1 & CYP1A2.

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Caffeine metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism