Cytochrome P450 26B (CYP26B1) Mouse Monoclonal Antibody [Clone ID: T5P3G2*A3]

CAT#: TA353121L

Mouse monoclonal Anti-Cytochrome P450 26B1 Clone T5P3G2*A3

Product Images

Western blot analysis of cell lysate overexpressing CYP26B1.

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  Immunohistochemistry staining of human colon carcinoma with clone T5P3G2*A3

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  Immunohistochemistry staining of normal tissue, colon carcinoma and secondary lesions. Clone T5P3G2*A3 can be used neat or 1/5 diluted; antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0

Specifications

Product Data

• Clone Name: T5P3G2*A3
• Applications: IHC, WB
• Recommended Dilution: IHC ; WB
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide DSNQNEILPE (C-terminal sequence)
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome P450 family 26 subfamily B member 1
• Database Link:
  NP_063938
  Entrez Gene 232174 MouseEntrez Gene 312495 RatEntrez Gene 56603 Human
  UniProt ID Q9NR63
• Background: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Synonyms: CYP26A2; P450RAI-2; P450RAI2; RHFCA

Reference Data

• Protein Families: Druggable Genome, P450
• Protein Pathways: Retinol metabolism