CYP39A1 Mouse Monoclonal Antibody [Clone ID: M30P6D6]

CAT#: TA353131L

Mouse monoclonal Anti-Cytochrome P450 39A1 Clone M30P6D6

Product Images

Western Blot using mAb M30P6D6

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  CYP39A1 used in lymph node metastatic Colorectal cancer

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  CYP39A1 used in normal colon mucosa

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  Immunohistochemistry: wax-embedded human liver

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  CYP39A1 used in primary Colorectal cancer

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Specifications

Product Data

• Clone Name: M30P6D6
• Applications: IHC, WB
• Recommended Dilution: ELISA ; IHC ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG3, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome P450 family 39 subfamily A member 1
• Database Link:
  NP_057677
  Entrez Gene 51302 Human
  UniProt ID Q9NYL5
• Background: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-α-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
• Synonyms: 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450; family 39; oxysterol 7-alpha-hydroxylase; oxysterol 7alpha-hydroxylase; polypeptide 1; subfamily a

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Primary bile acid biosynthesis