CYP51A1 Mouse Monoclonal Antibody [Clone ID: N6-P2H5*G8]

CAT#: TA353141L

Mouse monoclonal Anti-Cytochrome P450 51A1 Clone N6-P2H5*G8

Product Images

Western Blot analysis of pooled human liver microsomes with clone N6-P2H5*G8.

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  Photomicrograph of metastatic tissue IHC using N6-P2H5*G8

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  Photomicrograph of colon tissue IHC using N6-P2H5*G8

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  Photomicrograph of normal tissue IHC using N6-P2H5*G8

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  Photomicrograph of liver tissue IHC using N6-P2H5*G8

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  Photomicrograph of primary tumour IHC using N6-P2H5*G8

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Specifications

Product Data

• Clone Name: N6-P2H5*G8
• Applications: IHC, WB
• Recommended Dilution: ELISA ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide NPVIRYKRRS (C-terminal sequence).
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome P450 family 51 subfamily A member 1
• Database Link:
  NP_000777
  Entrez Gene 1595 Human
  UniProt ID Q16850
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
• Synonyms: CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
• Note: Unpurified, supplied as hybridoma supernatant.

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Metabolic pathways, Steroid biosynthesis