CYP7B1 Mouse Monoclonal Antibody [Clone ID: M17-P3F2]

CAT#: TA353142L

Mouse monoclonal Anti-Cytochrome P450 7B1 Clone M17-P3F2

Product Images

Western Blot analysis of pooled human liver microsomes with clone M17-P3F2.

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  Immunohistochemistry staining of human liver with clone M17-P3F2.

Specifications

Product Data

• Clone Name: M17-P3F2
• Applications: IHC, WB
• Recommended Dilution: ELISA ; IHC ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, lambda
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic peptide IQYPDSDVL (C-terminal sequence)
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytochrome P450 family 7 subfamily B member 1
• Database Link:
  NP_004811
  Entrez Gene 9420 Human
  UniProt ID O75881
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]
• Synonyms: CBAS3; CP7B; SPG5A

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Primary bile acid biosynthesis