CD32B (FCGR2B) Mouse Monoclonal Antibody [Clone ID: 2ZC115]

CAT#: TA353189L

Mouse monoclonal Anti-FCGR2 Clone 2ZC115

Specifications

Product Data

• Clone Name: 2ZC115
• Recommended Dilution: IHC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Hairy cell leukaemia cells
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fc fragment of IgG receptor IIb
• Database Link:
  NP_003992
  Entrez Gene 2213 Human
  UniProt ID P31994
• Background: Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.
• Synonyms: CD32; CD32B; FCG2; FCGR2; IGFR2
• Note: Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well.

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus