ICAM1 Mouse Monoclonal Antibody [Clone ID: P1W16]

CAT#: TA353227L

Mouse monoclonal Anti-ICAM1 Clone P1W16

Specifications

Product Data

• Clone Name: P1W16
• Recommended Dilution: FACS ; IHC ; IF ; IP
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: V(+)B2- Human Ocular melanoma line
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 85-115
• Gene Name: intercellular adhesion molecule 1
• Database Link:
  NP_000192
  Entrez Gene 3383 Human
  UniProt ID P05362
• Background: ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma.
• Synonyms: BB2; CD54; P3.58

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Viral myocarditis