CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: CD11C-100/D2]

CAT#: TA353267L

Mouse monoclonal Anti-CD11C Clone CD11C-100/D2

Specifications

Product Data

• Clone Name: CD11C-100/D2
• Recommended Dilution: IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSPPSEK
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit alpha X
• Database Link:
  NP_000878
  Entrez Gene 3687 Human
  UniProt ID P20702
• Background: The integrin alpha X chain protein (CD11c) belongs to the Ã?2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and Ã? subunit. CD11c (the a subunit) combines with CD18 (the Ã? subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.
• Synonyms: CD11C; SLEB6

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Regulation of actin cytoskeleton