Integrin beta 1 (ITGB1) Mouse Monoclonal Antibody [Clone ID: 12G10]

CAT#: TA353269L

Mouse monoclonal Anti-CD29 Clone 12G10

Specifications

Product Data

• Clone Name: 12G10
• Recommended Dilution: ELISA ; FACS ; IHC ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified human β1 integrin preparation from HT1080 fibrosarcoma cell extract.
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit beta 1
• Database Link:
  NP_002202
  Entrez Gene 3688 Human
  UniProt ID P05556
• Background: CD29 is a member of the family of integrins, membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
• Synonyms: CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB
• Note: 12G10 has been shown to recognize a ligand-induced binding site of human β1 integrin. The binding is increased in the presence of a

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Axon guidance, Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer