CD61 (ITGB3) Mouse Monoclonal Antibody [Clone ID: Y2/51]

CAT#: TA353275L

Mouse monoclonal Anti-Integrin b3 Clone Y2/51

Specifications

Product Data

• Clone Name: Y2/51
• Recommended Dilution: FACS ; IHC ; IF ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Phytohaemagglutin-stimulated peripheral blood cells
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit beta 3
• Database Link:
  NP_000203
  Entrez Gene 3690 Human
  UniProt ID P05106
• Background: CD61 is expressed by megakaryocytes, platelets and osteoclasts. Y2/51 is widely used as a marker of megakaryocytes in bone marrow trephines.
• Synonyms: BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT
• Note: Please note this cell line has not been weaned out of HAT. Ultroser G can be used at 1% if the cells are not growing well.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton