Cytokeratin 10 (KRT10) Mouse Monoclonal Antibody [Clone ID: LH2]

CAT#: TA353287L

Mouse monoclonal Anti-Keratin10 Clone LH2

Specifications

Product Data

• Clone Name: LH2
• Recommended Dilution: FACS ; IHC ; IF ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: extract of skin from psoriasis patient
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: keratin 10
• Database Link:
  NP_000412
  Entrez Gene 3858 Human
  UniProt ID P13645
• Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 10 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia and is present on all suprabasal keratinocytes. Mutations in keratin 10 cause epidermolytic hyperkeratosis. LH2 does not react with any tumour tissue regardless of histological classification.
• Synonyms: BCIE; BIE; CK10; EHK; K10; KPP
• Note: LH2 is monospecific and has high affinity.