Cytokeratin 16 (KRT16) Mouse Monoclonal Antibody [Clone ID: LL025]

CAT#: TA353293L

Mouse monoclonal Anti-Keratin16 Clone LL025

Specifications

Product Data

• Clone Name: LL025
• Recommended Dilution: IHC ; IF ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to an amino acid sequence of the carboxyl terminus of human keratin 16.
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: keratin 16
• Database Link:
  NP_005548
  Entrez Gene 3868 Human
  UniProt ID P08779
• Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 16 is expressed in suprabasal keratinocytes of wounded epidermis. Keratin 16 suprabasal expression is found in situations of high cell turnover. LL025 reactivity was completely negative in normal breast tissue and non-invasive breast carcinoma. However, 10% of the invasive carcinomas tested were diffusely or focally positive with this antibody.
• Synonyms: CK16; FNEPPK; K1CP; K16; KRT16A; NEPPK; PC1
• Note: Immunoperoxidase is recommended for use on frozen sections.