Cytokeratin 18 (KRT18) Mouse Monoclonal Antibody [Clone ID: LP34]

CAT#: TA353294L

Mouse monoclonal Anti-Keratin18 & 6 Clone LP34

Specifications

Product Data

• Clone Name: LP34
• Recommended Dilution: ELISA ; IHC ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human stratum corneum.
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 10
• Gene Name: keratin 18
• Database Link:
  NP_000215
  Entrez Gene 3875 Human
  UniProt ID P05783
• Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin. Keratin 18 is one of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratin 18 is a major component of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LP34 stains all human epithelial cells except for the inner hair root sheath and one or two other exceptional cell types.
• Synonyms: CYK18; K18

Reference Data

• Protein Pathways: Pathogenic Escherichia coli infection